Synthesis of Macroheterocycles through Intramolecular Oxidative Coupling of Furanoid β-Ketoesters
نویسندگان
چکیده
منابع مشابه
Synthesis of Novel Sterically Demanding Carbo- and Heterocyclic β-Ketoesters
We present an easy method for the synthesis of β-ketoesters starting from various carbocyclic and heterocyclic carboxylic acids and esters. The β-ketoester side-chain was introduced by a sequence involving α-deprotonation and quenching with CO2, conversion to the corresponding acid chloride and subsequent chain elongation using deprotonated ethyl acetate.
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15 صفحه اولPhoto-organocatalytic Enantioselective Perfluoroalkylation of β-Ketoesters
The visible-light-driven, phase-transfer-catalyzed, enantioselective perfluoroalkylation and trifluoromethylation of cyclic β-ketoesters is described. The photo-organocatalytic process, which occurs at ambient temperature and under visible light illumination, is triggered by the photochemical activity of in situ-generated electron donor-acceptor complexes, arising from the association of chiral...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2012
ISSN: 1433-7851
DOI: 10.1002/anie.201201538